Plasma cell-free DNA chromatin immunoprecipitation is associated with phenotypic and clinical heterogeneity in advanced prostate cancer
Cancer Research, 2024 (in press)
Joonatan Sipola†, Asli D. Munzur†, Edmond M. Kwan†, Clara C. Y. Seo, Benjamin J. Hauk, Matti Annala, Corinne Maurice-Dror, Kim N. Chi, Cameron Herberts*, Alexander W. Wyatt*, David Y. Takeda*.
Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping
Nature Cancer, 2023
Evan W. Warner†, Kim Van der Eecken†, Andrew J. Murtha†, Edmond M. Kwan, Cameron Herberts, Joonatan Sipola, Sarah W. S. Ng, Xinyi E. Chen, Nicolette M. Fonseca, Elie Ritch, Elena Schönlau, Cecily Q. Bernales, Gráinne Donnellan, Aslı D. Munzur, Karan Parekh, Kevin Beja, Amanda Wong, Sofie Verbeke, Nicolaas Lumen, Jo Van Dorpe, Bram De Laere, Matti Annala, Gillian Vandekerkhove, Piet Ost*, Alexander W. Wyatt*.
[177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial
The Lancet, 2021
Michael S. Hofman, Louise Emmett, Shahneen Sandhu, Amir Iravani, Anthony M. Joshua, Jeffrey C. Goh, David A. Pattison, Thean Hsiang Tan, Ian D. Kirkwood, Siobhan Ng, Roslyn J. Francis, Craig Gedye, Natalie K. Rutherford, Andrew Weickhardt , Andrew M. Scott, Sze-Ting Lee, Edmond M. Kwan, Arun A. Azad, Shakher Ramdave, Andrew D. Redfern, William Macdonald, Alex Guminski, Edward Hsiao, Wei Chua, Peter Lin, Alison Y. Zhang, Margaret M. McJannett, Martin R. Stockler, John A. Violet, Scott G. Williams, Andrew J. Martin, Ian D. Davis, for the TheraP Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials Group.
Avelumab combined with stereotactic ablative body radiotherapy in metastatic castration-resistant prostate cancer: the phase 2 ICE-PAC clinical trial
European Urology, 2022
Edmond M. Kwan, Lavinia Spain, Angelyn Anton, Chun L. Gan, Linda Garrett, Deborah Chang, Elizabeth Liow, Caitlin Bennett, Tiantian Zheng, Jianjun Yu, Chao Dai, Pan Du, Shidong Jia, Heidi Fettkeh, Claire Abou-Seif, Gargi Kothari, Mark Shaw, Phillip Parente, Carmel Pezaro, Ben Tran, Shankar Siva, Arun A. Azad.
Plasma cell–free DNA profiling of PTEN-PI3K-AKT pathway aberrations in metastatic castration-resistant prostate cancer
JCO Precision Oncology, 2022
Edmond M. Kwan†, Chao Dai†, Heidi Fettke†, Christine Hauser, Maria M. Docanto, Patricia Bukczynska, Nicole Ng, Siavash Foroughi, Lisa-Jane K. Graham, Kate Mahon, Winston Tan, Xiaohong Wang, Zhixin Zhao, Tiantian Zheng, Kemin Zhou, Jianjun Yu, Pan Du, Lisa G. Horvath, Shidong Jia, Manish Kohli, Arun A. Azad.
Prognostic utility of a whole-blood androgen receptor-based gene signature in metastatic castration-resistant prostate cancer
European Urology Focus, 2021
Edmond M. Kwan, Heidi Fettke, Maria M. Docanto, Sarah Q. To, Patricia Bukczynska, Andrew Mant, David Pook, Nicole Ng, Lisa-Jane K. Graham, Stefano Mangiola, Eva Segelov, Kate Mahon, Ian D. Davis, Phillip Parente, Carmel Pezaro, Tilman Todenhofer, Lisa G. Horvath, Arun A. Azad.
Combined cell-free DNA and RNA profiling of the androgen receptor: clinical utility of a novel multi-analyte liquid biopsy assay for metastatic prostate cancer European Urology, 2020
Heidi Fettke†, Edmond M. Kwan†, Maria M. Docanto, Patricia Bukczynska, Nicole Ng, Lisa-Jane K. Graham, Kate Mahon, Christine Hauser, Winston Tan, Xiao Hong Wang, Zhixin Zhao, Tiantian Zheng, Kemin Zhou, Pan Du, Jianjun Yu, Yong Huang, Shidong Jia, Manish Kohli, Lisa G. Horvath, Arun A. Azad.
